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According to research on wikipedia, it is very similar to Ketamine and was designed in part in an attempt to avoid the urotoxicity associated with ketamine abuse; it was thought the compound’s increased potency and reduced dose would limit the accumulation of urotoxic metabolites in the bladder.

Methoxetamine MXE has been found to produce bladder inflammation and fibrosis after high dose so, special care should be taken about the dose.

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Source: Holla Chemicals